Abstract Background Pichia pastoris is widely used as a production platform for heterologous proteins and model organism for organelle proliferation.Without a published genome sequence available, strain and process development relied mainly on analogies to other, well studied yeasts like Saccharomyces cerevisiae.Results To investigate specific feat
ABSTRACT Group A Streptococcus (GAS) can be internalized by epithelial cells, including keratinocytes from human skin or pharyngeal epithelium.Internalization of GAS by epithelial cells has been postulated both to play a role in host defense and to provide a sanctuary site for GAS survival.The cholesterol-binding cytolysin streptolysin O (SLO) appe
Radar detection and tracking of targets in the marine environment are common tasks performed to ensure the safe navigation of ships or monitor traffic in harbor areas.More recently, radar technology has been proposed to support the collision avoidance system of autonomous surface vehicles, which are characterized by severe constraints in terms of p
The paper is focused on the possibility of fabricating the alumina matrix ceramic-nickel composites with gradient concentration of metal particles.Centrifugal slip casting method was chosen for the composite fabrication.This method allows fabrication of the graded distribution of nickel particles in Armbands the hollow cylinder composites.The horiz
Olesoxime (TRO19622) is a novel mitochondrial-targeted neuroprotective compound undergoing a pivotal clinical efficacy study in Amyotrophic Lateral Sclerosis (ALS) and Hat also in development for Spinal Muscular Atrophy (SMA).It belongs to a new family of cholesterol-oximes identified for its survival-promoting activity on purified motor neurons de